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Access to indolines from primary phenylethylamines by an unexpected palladium-catalyzed C–H functionalization process

A new method for the preparation of 2,2-disubstituted indolines from 2-phenylethylamines was developed under Pd catalysis and PhI(OAc)(2) as oxidant. Imines derived from 2-pyridinecarboxaldehyde were formed in situ to direct a C–H activation process. The resulting imines were also oxidized to the co...

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Detalles Bibliográficos
Autores principales: Mancinelli, Andrea, Albert, Joan, Ariza, Xavier, Barrios, Leoní A., Garcia, Jordi, Gómez, Roberto, Granell, Jaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070636/
https://www.ncbi.nlm.nih.gov/pubmed/35529191
http://dx.doi.org/10.1039/c9ra05670j