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Access to indolines from primary phenylethylamines by an unexpected palladium-catalyzed C–H functionalization process
A new method for the preparation of 2,2-disubstituted indolines from 2-phenylethylamines was developed under Pd catalysis and PhI(OAc)(2) as oxidant. Imines derived from 2-pyridinecarboxaldehyde were formed in situ to direct a C–H activation process. The resulting imines were also oxidized to the co...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070636/ https://www.ncbi.nlm.nih.gov/pubmed/35529191 http://dx.doi.org/10.1039/c9ra05670j |