Synthesis and discovery of 18β-glycyrrhetinic acid derivatives inhibiting cancer stem cell properties in ovarian cancer cells

Despite advances in ovarian cancer treatment, the five-year overall survival rate is less than 30% with the presence of cancer stem cells (CSCs). To develop CSC-targeting therapy, a series of 18β-glycyrrhetinic acid (GA) derivatives containing cinnamamide moiety have been designed, synthesized, and...

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Detalles Bibliográficos
Autores principales: Li, Xiaojing, Liu, Yihua, Wang, Na, Liu, Yuyu, Wang, Shuai, Wang, Hongmin, Li, Aihua, Ren, Shaoda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070660/
https://www.ncbi.nlm.nih.gov/pubmed/35529208
http://dx.doi.org/10.1039/c9ra04961d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070660/
https://www.ncbi.nlm.nih.gov/pubmed/35529208
http://dx.doi.org/10.1039/c9ra04961d

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