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Rab40c regulates focal adhesions and PP6 activity by controlling ANKRD28 ubiquitylation

Rab40c is a SOCS box–containing protein which binds Cullin5 to form a ubiquitin E3 ligase complex (Rab40c/CRL5) to regulate protein ubiquitylation. However, the exact functions of Rab40c remain to be determined, and what proteins are the targets of Rab40c-Cullin5–mediated ubiquitylation in mammalian...

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Detalles Bibliográficos
Autores principales: Han, Ke-Jun, Mikalayeva, Valeryia, Gerber, Scott A, Kettenbach, Arminja N, Skeberdis, Vytenis A, Prekeris, Rytis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070665/
https://www.ncbi.nlm.nih.gov/pubmed/35512830
http://dx.doi.org/10.26508/lsa.202101346