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Sex-heterogeneous SNPs disproportionately influence gene expression and health

Phenotypic differences across sexes are pervasive, but the genetic architecture of sex differences within and across phenotypes is mostly unknown. In this study, we aimed to improve detection power for sex-differentially contributing SNPs previously demonstrated to be enriched in disease association...

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Detalles Bibliográficos
Autores principales: Traglia, Michela, Bout, Margaux, Weiss, Lauren A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070888/
https://www.ncbi.nlm.nih.gov/pubmed/35511767
http://dx.doi.org/10.1371/journal.pgen.1010147