Triphala inhibits alpha-synuclein fibrillization and their interaction study by NMR provides insights into the self-association of the protein

The process of assembly and accumulation of the intrinsically disordered protein (IDP), alpha-synuclein (αSyn) into amyloid fibrils is a pathogenic process leading to several neurodegenerative disorders such as Parkinson's disease, multiple system atrophy and others. Although several molecules...

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Detalles Bibliográficos
Autores principales: Bopardikar, Mandar, Bhattacharya, Anusri, Rao Kakita, Veera Mohana, Rachineni, Kavitha, Borde, Lalit C., Choudhary, Sinjan, Koti Ainavarapu, Sri Rama, Hosur, Ramakrishna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071048/
https://www.ncbi.nlm.nih.gov/pubmed/35529629
http://dx.doi.org/10.1039/c9ra05551g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071048/
https://www.ncbi.nlm.nih.gov/pubmed/35529629
http://dx.doi.org/10.1039/c9ra05551g

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