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Triphala inhibits alpha-synuclein fibrillization and their interaction study by NMR provides insights into the self-association of the protein
The process of assembly and accumulation of the intrinsically disordered protein (IDP), alpha-synuclein (αSyn) into amyloid fibrils is a pathogenic process leading to several neurodegenerative disorders such as Parkinson's disease, multiple system atrophy and others. Although several molecules...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071048/ https://www.ncbi.nlm.nih.gov/pubmed/35529629 http://dx.doi.org/10.1039/c9ra05551g |