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Use of the EpiDerm(TM) 3D reconstructed skin micronucleus assay for fragrance materials

In order to evaluate the utility of the 3D reconstructed skin micronucleus assay (3DRSMN) to assess clastogenic/aneugenic potential of the fragrance chemicals, a set of 22 fragrance materials were evaluated in 3DRSMN assay. These materials evaluated were also evaluated in an in vitro as well as in v...

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Detalles Bibliográficos
Autores principales: Thakkar, Yax, Moustakas, Holger, Aardema, Marilyn, Roy, Shambhu, Pfuhler, Stefan, Api, Anne Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071073/
https://www.ncbi.nlm.nih.gov/pubmed/34850913
http://dx.doi.org/10.1093/mutage/geab040