Cargando…
Use of the EpiDerm(TM) 3D reconstructed skin micronucleus assay for fragrance materials
In order to evaluate the utility of the 3D reconstructed skin micronucleus assay (3DRSMN) to assess clastogenic/aneugenic potential of the fragrance chemicals, a set of 22 fragrance materials were evaluated in 3DRSMN assay. These materials evaluated were also evaluated in an in vitro as well as in v...
Autores principales: | Thakkar, Yax, Moustakas, Holger, Aardema, Marilyn, Roy, Shambhu, Pfuhler, Stefan, Api, Anne Marie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071073/ https://www.ncbi.nlm.nih.gov/pubmed/34850913 http://dx.doi.org/10.1093/mutage/geab040 |
Ejemplares similares
-
Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses
por: Chapman, K. E., et al.
Publicado: (2014) -
The BlueScreen HC assay to predict the genotoxic potential of fragrance materials
por: Thakkar, Yax, et al.
Publicado: (2022) -
Validation of the 3D reconstructed human skin micronucleus (RSMN) assay: an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays
por: Pfuhler, Stefan, et al.
Publicado: (2021) -
Skin Corrosion and Irritation Test of Nanoparticles Using Reconstructed Three-Dimensional Human Skin Model, EpiDerm(TM)
por: Kim, Hyejin, et al.
Publicado: (2016) -
Comet assay in reconstructed 3D human epidermal skin models—investigation of intra- and inter-laboratory reproducibility with coded chemicals
por: Reus, Astrid A., et al.
Publicado: (2013)