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DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies

BACKGROUND: DNA damage is a hazard that affects all cells of the body. DNA-damage repair (DDR) mechanisms are in place to repair damage and restore cellular function, as are other damage-induced processes such as apoptosis, autophagy and senescence. The resilience of germ cells and embryos in respon...

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Detalles Bibliográficos
Autores principales: Musson, Richard, Gąsior, Łukasz, Bisogno, Simona, Ptak, Grażyna Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071077/
https://www.ncbi.nlm.nih.gov/pubmed/35021196
http://dx.doi.org/10.1093/humupd/dmab046