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DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies
BACKGROUND: DNA damage is a hazard that affects all cells of the body. DNA-damage repair (DDR) mechanisms are in place to repair damage and restore cellular function, as are other damage-induced processes such as apoptosis, autophagy and senescence. The resilience of germ cells and embryos in respon...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071077/ https://www.ncbi.nlm.nih.gov/pubmed/35021196 http://dx.doi.org/10.1093/humupd/dmab046 |