Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters

In vitro assessment of mutagenicity is an essential component in the chemical risk assessment. Given the diverse modes of action by which chemicals can induce DNA damage, it is essential that these in vitro assays are carefully evaluated for their possibilities and limitations. In this study, we use...

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Detalles Bibliográficos
Autores principales: ter Braak, Bas, Niemeijer, Marije, Wolters, Liesanne, Le Dévédec, Sylvia, Bouwman, Peter, van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Manuscripts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071099/
https://www.ncbi.nlm.nih.gov/pubmed/34448005
http://dx.doi.org/10.1093/mutage/geab031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071099/
https://www.ncbi.nlm.nih.gov/pubmed/34448005
http://dx.doi.org/10.1093/mutage/geab031

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