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Impact of an aryl bulky group on a one-pot reaction of aldehyde with malononitrile and N-substituted 2-cyanoacetamide

In this study, we successfully explored the effect of steric hindrance on the one-pot reaction of different aryl aldehydes with malononitrile and N-substituted 2-cyanoacetamide in the presence of piperidinium acetate as the catalyst. It involved the Knoevenagel condensation of the aldehyde and malon...

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Detalles Bibliográficos
Autores principales: Vala, Ruturajsinh M., Patel, Divyang M., Sharma, Mayank G., Patel, Hitendra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071202/
https://www.ncbi.nlm.nih.gov/pubmed/35529659
http://dx.doi.org/10.1039/c9ra05975j