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1,1-Difluoroethyl chloride (CH(3)CF(2)Cl), a novel difluoroalkylating reagent for 1,1-difluoroethylation of arylboronic acids
1,1-Difluoroethylated aromatics are of great importance in medicinal chemistry and related fields. 1,1-Difluoroethyl chloride (CH(3)CF(2)Cl), a cheap and abundant industrial raw material, is viewed as an ideal 1,1-difluoroethylating reagent, but the direct introduction of the difluoroethyl (CF(2)CH(...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071211/ https://www.ncbi.nlm.nih.gov/pubmed/35529618 http://dx.doi.org/10.1039/c9ra06406k |