1,1-Difluoroethyl chloride (CH(3)CF(2)Cl), a novel difluoroalkylating reagent for 1,1-difluoroethylation of arylboronic acids

1,1-Difluoroethylated aromatics are of great importance in medicinal chemistry and related fields. 1,1-Difluoroethyl chloride (CH(3)CF(2)Cl), a cheap and abundant industrial raw material, is viewed as an ideal 1,1-difluoroethylating reagent, but the direct introduction of the difluoroethyl (CF(2)CH(...

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Detalles Bibliográficos
Autores principales: Liu, Jianchang, Zhang, Jida, Wu, Chaolin, Liu, Hefu, Liu, Hui, Sun, Fenggang, Li, Yueyun, Liu, Yuying, Dong, Yunhui, Li, Xinjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071211/
https://www.ncbi.nlm.nih.gov/pubmed/35529618
http://dx.doi.org/10.1039/c9ra06406k

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