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The role of Alzheimer’s disease risk genes in endolysosomal pathways

There is ample pathological and biological evidence for endo-lysosomal dysfunction in Alzheimer’s disease (AD) and emerging genetic studies repeatedly implicate endo-lysosomal genes as associated with increased AD risk. The endo-lysosomal network (ELN) is essential for all cell types of the central...

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Detalles Bibliográficos
Autores principales: Szabo, Marcell P., Mishra, Swati, Knupp, Allison, Young, Jessica E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071255/
https://www.ncbi.nlm.nih.gov/pubmed/34871734
http://dx.doi.org/10.1016/j.nbd.2021.105576