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Enhanced C/EBPβ function promotes hyperplastic versus hypertrophic fat tissue growth and prevents steatosis in response to high-fat diet feeding

Chronic obesity is correlated with severe metabolic and cardiovascular diseases as well as with an increased risk for developing cancers. Obesity is usually characterized by fat accumulation in enlarged – hypertrophic – adipocytes that are a source of inflammatory mediators, which promote the develo...

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Detalles Bibliográficos
Autores principales: Müller, Christine, Zidek, Laura M, Eichwald, Sabrina, Kortman, Gertrud, Koster, Mirjam H, Calkhoven, Cornelis F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071262/
https://www.ncbi.nlm.nih.gov/pubmed/35451956
http://dx.doi.org/10.7554/eLife.62625