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Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence

Microglia serve critical remodeling roles that shape the developing nervous system, responding to the changing neural environment with phagocytosis or soluble factor secretion. Recent single-cell sequencing (scRNAseq) studies have revealed the context-dependent diversity in microglial properties and...

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Detalles Bibliográficos
Autores principales: Anderson, Sarah Rose, Roberts, Jacqueline M, Ghena, Nathaniel, Irvin, Emmalyn A, Schwakopf, Joon, Cooperstein, Isabelle B, Bosco, Alejandra, Vetter, Monica L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071266/
https://www.ncbi.nlm.nih.gov/pubmed/35481836
http://dx.doi.org/10.7554/eLife.76564