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Visualization of ligand-induced c-MYC duplex–quadruplex transition and direct exploration of the altered c-MYC DNA-protein interactions in cells

Ligand-Induced duplex-quadruplex transition within the c-MYC promoter region is one of the most studied and advanced ideas for c-MYC regulation. Despite its importance, there is a lack of methods for monitoring such process in cells, hindering a better understanding of the essence of c-MYC G-quadrup...

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Detalles Bibliográficos
Autores principales: Yuan, Jia-Hao, Tu, Jia-Li, Liu, Guo-Cai, Chen, Xiu-Cai, Huang, Zhi-Shu, Chen, Shuo-Bin, Tan, Jia-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071431/
https://www.ncbi.nlm.nih.gov/pubmed/35412611
http://dx.doi.org/10.1093/nar/gkac245