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Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose–response study designs

The application of single-cell RNA sequencing (scRNAseq) for the evaluation of chemicals, drugs, and food contaminants presents the opportunity to consider cellular heterogeneity in pharmacological and toxicological responses. Current differential gene expression analysis (DGEA) methods focus primar...

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Detalles Bibliográficos
Autores principales: Nault, Rance, Saha, Satabdi, Bhattacharya, Sudin, Dodson, Jack, Sinha, Samiran, Maiti, Tapabrata, Zacharewski, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071439/
https://www.ncbi.nlm.nih.gov/pubmed/35061903
http://dx.doi.org/10.1093/nar/gkac019