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Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose–response study designs
The application of single-cell RNA sequencing (scRNAseq) for the evaluation of chemicals, drugs, and food contaminants presents the opportunity to consider cellular heterogeneity in pharmacological and toxicological responses. Current differential gene expression analysis (DGEA) methods focus primar...
Autores principales: | Nault, Rance, Saha, Satabdi, Bhattacharya, Sudin, Dodson, Jack, Sinha, Samiran, Maiti, Tapabrata, Zacharewski, Tim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071439/ https://www.ncbi.nlm.nih.gov/pubmed/35061903 http://dx.doi.org/10.1093/nar/gkac019 |
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