Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biology

We have identified seven putative guanine quadruplexes (G4) in the RNA genome of tick-borne encephalitis virus (TBEV), a flavivirus causing thousands of human infections and numerous deaths every year. The formation of G4s was confirmed by biophysical methods on synthetic oligonucleotides derived fr...

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Detalles Bibliográficos
Autores principales: Holoubek, Jiří, Bednářová, Klára, Haviernik, Jan, Huvarová, Ivana, Dvořáková, Zuzana, Černý, Jiří, Outlá, Martina, Salát, Jiří, Konkol'ová, Eva, Boura, Evzen, Růžek, Daniel, Vorlíčková, Michaela, Eyer, Luděk, Renčiuk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071444/
https://www.ncbi.nlm.nih.gov/pubmed/35420134
http://dx.doi.org/10.1093/nar/gkac225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071444/
https://www.ncbi.nlm.nih.gov/pubmed/35420134
http://dx.doi.org/10.1093/nar/gkac225

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