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Nuclear and cytoplasmic poly(A) binding proteins (PABPs) favor distinct transcripts and isoforms
The poly(A)-tail appended to the 3′-end of most eukaryotic transcripts plays a key role in their stability, nuclear transport, and translation. These roles are largely mediated by Poly(A) Binding Proteins (PABPs) that coat poly(A)-tails and interact with various proteins involved in the biogenesis a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071453/ https://www.ncbi.nlm.nih.gov/pubmed/35438785 http://dx.doi.org/10.1093/nar/gkac263 |