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Nuclear and cytoplasmic poly(A) binding proteins (PABPs) favor distinct transcripts and isoforms

The poly(A)-tail appended to the 3′-end of most eukaryotic transcripts plays a key role in their stability, nuclear transport, and translation. These roles are largely mediated by Poly(A) Binding Proteins (PABPs) that coat poly(A)-tails and interact with various proteins involved in the biogenesis a...

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Detalles Bibliográficos
Autores principales: Nicholson-Shaw, Angela L, Kofman, Eric R, Yeo, Gene W, Pasquinelli, Amy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071453/
https://www.ncbi.nlm.nih.gov/pubmed/35438785
http://dx.doi.org/10.1093/nar/gkac263