Holliday junction resolution by At-HIGLE: an SLX1 lineage endonuclease from Arabidopsis thaliana with a novel in-built regulatory mechanism

Holliday junction is the key homologous recombination intermediate, resolved by structure-selective endonucleases (SSEs). SLX1 is the most promiscuous SSE of the GIY-YIG nuclease superfamily. In fungi and animals, SLX1 nuclease activity relies on a non-enzymatic partner, SLX4, but no SLX1-SLX4 like...

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Detalles Bibliográficos
Autores principales: Verma, Prabha, Kumari, Poonam, Negi, Shreya, Yadav, Gitanjali, Gaur, Vineet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071465/
https://www.ncbi.nlm.nih.gov/pubmed/35412622
http://dx.doi.org/10.1093/nar/gkac239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071465/
https://www.ncbi.nlm.nih.gov/pubmed/35412622
http://dx.doi.org/10.1093/nar/gkac239

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