Psoralen mapping reveals a bacterial genome supercoiling landscape dominated by transcription

DNA supercoiling is a key regulator of all DNA metabolic processes including replication, transcription, and recombination, yet a reliable genomic assay for supercoiling is lacking. Here, we present a robust and flexible method (Psora-seq) to measure whole-genome supercoiling at high resolution. Usi...

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Detalles Bibliográficos
Autores principales: Visser, Bryan J, Sharma, Sonum, Chen, Po J, McMullin, Anna B, Bates, Maia L, Bates, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071471/
https://www.ncbi.nlm.nih.gov/pubmed/35420137
http://dx.doi.org/10.1093/nar/gkac244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071471/
https://www.ncbi.nlm.nih.gov/pubmed/35420137
http://dx.doi.org/10.1093/nar/gkac244

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