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Chemical biology and medicinal chemistry of RNA methyltransferases

RNA methyltransferases (MTases) are ubiquitous enzymes whose hitherto low profile in medicinal chemistry, contrasts with the surging interest in RNA methylation, the arguably most important aspect of the new field of epitranscriptomics. As MTases become validated as drug targets in all major fields...

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Detalles Bibliográficos
Autores principales: Fischer, Tim R, Meidner, Laurenz, Schwickert, Marvin, Weber, Marlies, Zimmermann, Robert A, Kersten, Christian, Schirmeister, Tanja, Helm, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071492/
https://www.ncbi.nlm.nih.gov/pubmed/35412633
http://dx.doi.org/10.1093/nar/gkac224