Phosphorylated MED1 links transcription recycling and cancer growth

Mediator activates RNA polymerase II (Pol II) function during transcription, but it remains unclear whether Mediator is able to travel with Pol II and regulate Pol II transcription beyond the initiation and early elongation steps. By using in vitro and in vivo transcription recycling assays, we find...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Zhong, Ye, Zhenqing, Soccio, Raymond E, Nakadai, Tomoyoshi, Hankey, William, Zhao, Yue, Huang, Furong, Yuan, Fuwen, Wang, Hongyan, Cui, Zhifen, Sunkel, Benjamin, Wu, Dayong, Dzeng, Richard K, Thomas-Ahner, Jennifer M, Huang, Tim H M, Clinton, Steven K, Huang, Jiaoti, Lazar, Mitchell A, Jin, Victor X, Roeder, Robert G, Wang, Qianben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071494/
https://www.ncbi.nlm.nih.gov/pubmed/35394046
http://dx.doi.org/10.1093/nar/gkac246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071494/
https://www.ncbi.nlm.nih.gov/pubmed/35394046
http://dx.doi.org/10.1093/nar/gkac246

Ejemplares similares