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Noggin proteins are multifunctional extracellular regulators of cell signaling

Noggin is an extracellular cysteine knot protein that plays a crucial role in vertebrate dorsoventral patterning. Noggin binds and inhibits the activity of bone morphogenetic proteins via a conserved N-terminal clip domain. Noncanonical orthologs of Noggin that lack a clip domain (“Noggin-like” prot...

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Detalles Bibliográficos
Autores principales: Karunaraj, Prashath, Tidswell, Olivia, Duncan, Elizabeth J, Lovegrove, Mackenzie R, Jefferies, Grace, Johnson, Travis K, Beck, Caroline W, Dearden, Peter K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071555/
https://www.ncbi.nlm.nih.gov/pubmed/35357435
http://dx.doi.org/10.1093/genetics/iyac049