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Siglec-1 expression on monocytes is associated with the interferon signature in juvenile dermatomyositis and can predict treatment response

OBJECTIVE: JDM is a rare chronic immune-mediated inflammatory disease with a predominant role for type I IFN responses. We aimed to determine the potential of Siglec-1 expression on monocytes as a novel IFN-inducible biomarker for disease activity monitoring and prediction of treatment response in p...

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Detalles Bibliográficos
Autores principales: Lerkvaleekul, Butsabong, Veldkamp, Saskia R, van der Wal, M Marlot, Schatorjé, Ellen J H, Kamphuis, Sylvia S M, van den Berg, J Merlijn, Hissink Muller, Petra C E, Armbrust, Wineke, Vastert, Sebastiaan J, Wienke, Judith, Jansen, Marc H A, van Royen-Kerkhof, Annet, van Wijk, Femke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071568/
https://www.ncbi.nlm.nih.gov/pubmed/34387304
http://dx.doi.org/10.1093/rheumatology/keab601