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Design, synthesis and biological evaluation of 1,2,3-triazole based 2-aminobenzimidazoles as novel inhibitors of LasR dependent quorum sensing in Pseudomonas aeruginosa

Bacteria regulate their phenotype, growth and population via a signalling pathway known as quorum sensing. In this process, bacteria produce signalling molecules (autoinducers) to recognize their population density. Inhibiting this quorum sensing signalling pathway is one of the potential methods to...

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Detalles Bibliográficos
Autores principales: Srinivasarao, Singireddi, Nandikolla, Adinarayana, Nizalapur, Shashidhar, Yu, Tsz Tin, Pulya, Sravani, Ghosh, Balaram, Murugesan, Sankaranarayanan, Kumar, Naresh, Chandra Sekhar, Kondapalli Venkata Gowri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071802/
https://www.ncbi.nlm.nih.gov/pubmed/35528444
http://dx.doi.org/10.1039/c9ra05059k