Formal synthesis of (+)-lactacystin from l-serine

A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-l-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.

Detalles Bibliográficos
Autores principales: Bulman Page, Philip C., Goodyear, Ross L., Chan, Yohan, Slawin, Alexandra M. Z., Allin, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072140/
https://www.ncbi.nlm.nih.gov/pubmed/35531531
http://dx.doi.org/10.1039/c9ra07244f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072140/
https://www.ncbi.nlm.nih.gov/pubmed/35531531
http://dx.doi.org/10.1039/c9ra07244f

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