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Formal synthesis of (+)-lactacystin from l-serine
A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-l-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.
Autores principales: | Bulman Page, Philip C., Goodyear, Ross L., Chan, Yohan, Slawin, Alexandra M. Z., Allin, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072140/ https://www.ncbi.nlm.nih.gov/pubmed/35531531 http://dx.doi.org/10.1039/c9ra07244f |
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