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The upregulated intestinal folate transporters direct the uptake of ligand-modified nanoparticles for enhanced oral insulin delivery

Transporters are traditionally considered to transport small molecules rather than large-sized nanoparticles due to their small pores. In this study, we demonstrate that the upregulated intestinal transporter (PCFT), which reaches a maximum of 12.3-fold expression in the intestinal epithelial cells...

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Detalles Bibliográficos
Autores principales: Li, Jingyi, Zhang, Yaqi, Yu, Miaorong, Wang, Aohua, Qiu, Yu, Fan, Weiwei, Hovgaard, Lars, Yang, Mingshi, Li, Yiming, Wang, Rui, Li, Xiuying, Gan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072239/
https://www.ncbi.nlm.nih.gov/pubmed/35530154
http://dx.doi.org/10.1016/j.apsb.2021.07.024