Computational design of enhanced detoxification activity of a zearalenone lactonase from Clonostachys rosea in acidic medium

Computational design of pH-activity profiles for enzymes is of great importance in industrial applications. In this research, a computational strategy was developed to engineer the pH-activity profile of a zearalenone lactonase (ZHD101) from Clonostachys rosea to promote its activity in acidic mediu...

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Detalles Bibliográficos
Autores principales: Lin, Min, Tan, Jian, Xu, Zhaobin, Huang, Jin, Tian, Ye, Chen, Bo, Wu, Yandong, Tong, Yi, Zhu, Yushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072336/
https://www.ncbi.nlm.nih.gov/pubmed/35527979
http://dx.doi.org/10.1039/c9ra04964a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072336/
https://www.ncbi.nlm.nih.gov/pubmed/35527979
http://dx.doi.org/10.1039/c9ra04964a

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