Evidence against a contribution of the CCAAT-enhancer binding protein homologous protein (CHOP) in mediating neurotoxicity in rTg4510 mice

Tau accumulation and progressive loss of neurons are associated with Alzheimer’s disease (AD). Aggregation of tau has been associated with endoplasmic reticulum (ER) stress and the activation of the unfolded protein response (UPR). While ER stress and the UPR have been linked to AD, the contribution...

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Detalles Bibliográficos
Autores principales: Criado-Marrero, Marangelie, Blazier, Danielle M., Gould, Lauren A., Gebru, Niat T., Rodriguez Ospina, Santiago, Armendariz, Debra S., Darling, April L., Beaulieu-Abdelahad, David, Blair, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072347/
https://www.ncbi.nlm.nih.gov/pubmed/35513476
http://dx.doi.org/10.1038/s41598-022-11025-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072347/
https://www.ncbi.nlm.nih.gov/pubmed/35513476
http://dx.doi.org/10.1038/s41598-022-11025-x

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