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Evidence against a contribution of the CCAAT-enhancer binding protein homologous protein (CHOP) in mediating neurotoxicity in rTg4510 mice
Tau accumulation and progressive loss of neurons are associated with Alzheimer’s disease (AD). Aggregation of tau has been associated with endoplasmic reticulum (ER) stress and the activation of the unfolded protein response (UPR). While ER stress and the UPR have been linked to AD, the contribution...
Autores principales: | Criado-Marrero, Marangelie, Blazier, Danielle M., Gould, Lauren A., Gebru, Niat T., Rodriguez Ospina, Santiago, Armendariz, Debra S., Darling, April L., Beaulieu-Abdelahad, David, Blair, Laura J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072347/ https://www.ncbi.nlm.nih.gov/pubmed/35513476 http://dx.doi.org/10.1038/s41598-022-11025-x |
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