Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice

Transmission of epigenetic information between generations occurs in nematodes, flies and plants, mediated by specialised small RNA pathways, modified histones and DNA methylation. Similar processes in mammals can also affect phenotype through intergenerational or trans-generational mechanisms. Here...

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Detalles Bibliográficos
Autores principales: Van de Pette, Mathew, Dimond, Andrew, Galvão, António M., Millership, Steven J., To, Wilson, Prodani, Chiara, McNamara, Gráinne, Bruno, Ludovica, Sardini, Alessandro, Webster, Zoe, McGinty, James, French, Paul M. W., Uren, Anthony G., Castillo-Fernandez, Juan, Watkinson, William, Ferguson-Smith, Anne C., Merkenschlager, Matthias, John, Rosalind M., Kelsey, Gavin, Fisher, Amanda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072353/
https://www.ncbi.nlm.nih.gov/pubmed/35513363
http://dx.doi.org/10.1038/s41467-022-30022-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072353/
https://www.ncbi.nlm.nih.gov/pubmed/35513363
http://dx.doi.org/10.1038/s41467-022-30022-2

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