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Developmental mRNA m(5)C landscape and regulatory innovations of massive m(5)C modification of maternal mRNAs in animals

m(5)C is one of the longest-known RNA modifications, however, its developmental dynamics, functions, and evolution in mRNAs remain largely unknown. Here, we generate quantitative mRNA m(5)C maps at different stages of development in 6 vertebrate and invertebrate species and find convergent and unexp...

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Detalles Bibliográficos
Autores principales: Liu, Jianheng, Huang, Tao, Chen, Wanying, Ding, Chenhui, Zhao, Tianxuan, Zhao, Xueni, Cai, Bing, Zhang, Yusen, Li, Song, Zhang, Ling, Xue, Maoguang, He, Xiuju, Ge, Wanzhong, Zhou, Canquan, Xu, Yanwen, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072368/
https://www.ncbi.nlm.nih.gov/pubmed/35513466
http://dx.doi.org/10.1038/s41467-022-30210-0