Rad51-mediated replication of damaged templates relies on monoSUMOylated DDK kinase

DNA damage tolerance (DDT), activated by replication stress during genome replication, is mediated by translesion synthesis and homologous recombination (HR). Here we uncover that DDK kinase, essential for replication initiation, is critical for replication-associated recombination-mediated DDT. DDK...

Descripción completa

Detalles Bibliográficos
Autores principales: Joseph, Chinnu Rose, Dusi, Sabrina, Giannattasio, Michele, Branzei, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072374/
https://www.ncbi.nlm.nih.gov/pubmed/35513396
http://dx.doi.org/10.1038/s41467-022-30215-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072374/
https://www.ncbi.nlm.nih.gov/pubmed/35513396
http://dx.doi.org/10.1038/s41467-022-30215-9

Ejemplares similares