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SAPAP3 regulates epileptic seizures involving GluN2A in post-synaptic densities

Aberrantly synchronized neuronal discharges in the brain lead to epilepsy, a devastating neurological disease whose pathogenesis and mechanism are unclear. SAPAP3, a cytoskeletal protein expressed at high levels in the postsynaptic density (PSD) of excitatory synapses, has been well studied in the s...

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Detalles Bibliográficos
Autores principales: Zhang, Yanke, Wu, Junhong, Yan, Yin, Gu, Yixue, Ma, Yuanlin, Wang, Min, Zhang, Hui, Tao, Kaiyan, Lü, Yang, Yu, Weihua, Jing, Wei, Wang, Xuefeng, Tian, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072407/
https://www.ncbi.nlm.nih.gov/pubmed/35513389
http://dx.doi.org/10.1038/s41419-022-04876-9