Population pharmacokinetic analysis of sildenafil in term and preterm infants with pulmonary arterial hypertension

Sildenafil is widely used off-label in pediatric patients with pulmonary arterial hypertension (PAH). This study was conducted to characterize the pharmacokinetics (PK) of sildenafil in term and preterm neonates with PAH, by developing a population PK model, and to suggest appropriate doses to achie...

Descripción completa

Detalles Bibliográficos
Autores principales: Rhee, Su-jin, Shin, Seung Han, Oh, Jaeseong, Jung, Young Hwa, Choi, Chang Won, Kim, Han-Suk, Yu, Kyung-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072418/
https://www.ncbi.nlm.nih.gov/pubmed/35513541
http://dx.doi.org/10.1038/s41598-022-11038-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072418/
https://www.ncbi.nlm.nih.gov/pubmed/35513541
http://dx.doi.org/10.1038/s41598-022-11038-6

Ejemplares similares