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Population pharmacokinetic analysis of sildenafil in term and preterm infants with pulmonary arterial hypertension

Sildenafil is widely used off-label in pediatric patients with pulmonary arterial hypertension (PAH). This study was conducted to characterize the pharmacokinetics (PK) of sildenafil in term and preterm neonates with PAH, by developing a population PK model, and to suggest appropriate doses to achie...

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Detalles Bibliográficos
Autores principales:	Rhee, Su-jin, Shin, Seung Han, Oh, Jaeseong, Jung, Young Hwa, Choi, Chang Won, Kim, Han-Suk, Yu, Kyung-Sang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072418/ https://www.ncbi.nlm.nih.gov/pubmed/35513541 http://dx.doi.org/10.1038/s41598-022-11038-6

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