A genome on shaky ground: exploring the impact of mitochondrial DNA integrity on Parkinson’s disease by highlighting the use of cybrid models

Mitochondria play important roles in the regulation of key cellular processes, including energy metabolism, oxidative stress response, and signaling towards cell death or survival, and are distinguished by carrying their own genome (mtDNA). Mitochondrial dysfunction has emerged as a prominent cellul...

Descripción completa

Detalles Bibliográficos
Autores principales: Lang, Martin, Grünewald, Anne, Pramstaller, Peter P., Hicks, Andrew A., Pichler, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072496/
https://www.ncbi.nlm.nih.gov/pubmed/35513611
http://dx.doi.org/10.1007/s00018-022-04304-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072496/
https://www.ncbi.nlm.nih.gov/pubmed/35513611
http://dx.doi.org/10.1007/s00018-022-04304-3

Ejemplares similares