Encapsulation of echinomycin in cyclodextrin inclusion complexes into liposomes: in vitro anti-proliferative and anti-invasive activity in glioblastoma

Echinomycin, a DNA bis-intercalator peptide, belongs to the family of quinoxaline antibiotics. Echinomycin exhibits potent antitumor and antimicrobial activity. However, it is highly water insoluble and suffers from low bioavailability and unwanted side effects. Therefore, developing new formulation...

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Detalles Bibliográficos
Autores principales: Alshaer, Walhan, Zraikat, Manar, Amer, Amer, Nsairat, Hamdi, Lafi, Zainab, Alqudah, Dana A., Al Qadi, Enas, Alsheleh, Tasneem, Odeh, Fadwa, Alkaraki, Arwa, Zihlif, Malek, Bustanji, Yasser, Fattal, Elias, Awidi, Abdalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072562/
https://www.ncbi.nlm.nih.gov/pubmed/35529392
http://dx.doi.org/10.1039/c9ra05636j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072562/
https://www.ncbi.nlm.nih.gov/pubmed/35529392
http://dx.doi.org/10.1039/c9ra05636j

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