Combinatorial synthesis and biological evaluations of (E)-β-trifluoromethyl vinylsulfones as antitumor agents

Combinatorial synthesis of (E)-β-trifluoromethyl vinylsulfones is accomplished through a reaction of alkynes, Togni reagent, and sodium benzenesulfinates in DMSO under metal-free conditions at room temperature. These compounds are evaluated in several assays against different tumor cells. Some hits...

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Detalles Bibliográficos
Autores principales: Tang, Haosha, Kuang, Yunyan, Zeng, Julan, Li, Xiaofang, Zhou, Wei, Lu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072619/
https://www.ncbi.nlm.nih.gov/pubmed/35527921
http://dx.doi.org/10.1039/c9ra06368d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072619/
https://www.ncbi.nlm.nih.gov/pubmed/35527921
http://dx.doi.org/10.1039/c9ra06368d

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