Cargando…

Declining Levels and Bioavailability of IGF-I in Cardiovascular Aging Associate With QT Prolongation–Results From the 1946 British Birth Cohort

BACKGROUND: As people age, circulating levels of insulin-like growth factors (IGFs) and IGF binding protein 3 (IGFBP-3) decline. In rat cardiomyocytes, IGF-I has been shown to regulate sarcolemmal potassium channel activity and late sodium current thus impacting cardiac repolarization and the heart...

Descripción completa

Detalles Bibliográficos
Autores principales:	Charalambous, Christos, Moon, James C., Holly, Jeff M. P., Chaturvedi, Nishi, Hughes, Alun D., Captur, Gabriella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072634/ https://www.ncbi.nlm.nih.gov/pubmed/35528832 http://dx.doi.org/10.3389/fcvm.2022.863988

Ejemplares similares

Midlife blood pressure change and left ventricular mass and remodelling in older age in the 1946 British birth cohort study(†)
por: Ghosh, Arjun K., et al.
Publicado: (2014)

QT Prolongation in Cancer Patients
por: Kim, Peter, et al.
Publicado: (2021)

Patterns of adiposity, vascular phenotypes and cognitive function in the 1946 British Birth Cohort
por: Masi, Stefano, et al.
Publicado: (2018)

Socioeconomic inequalities in prevalence and development of multimorbidity across adulthood: A longitudinal analysis of the MRC 1946 National Survey of Health and Development in the UK
por: Khanolkar, Amal R., et al.
Publicado: (2021)

Longitudinal birth cohort study finds that life-course frailty associates with later-life heart size and function
por: Topriceanu, Constantin-Cristian, et al.
Publicado: (2021)

Early Morning QT Prolongation During Hypoglycemia: Only a Matter of Glucose?
por: D'Imperio, Sara, et al.
Publicado: (2021)

Diet and glycosylated haemoglobin in the 1946 British birth cohort
por: Prynne, CJ, et al.
Publicado: (2009)

Association of QT interval-prolonging drugs with clinical trial eligibility in patients with advanced cancer
por: Rowe, Elizabeth J., et al.
Publicado: (2022)

Life Course Socioeconomic Position: Associations with Cardiac Structure and Function at Age 60-64 Years in the 1946 British Birth Cohort
por: Murray, Emily T., et al.
Publicado: (2016)

Novel coronary heart disease risk factors at 60–64 years and life course socioeconomic position: The 1946 British birth cohort
por: Jones, Rebecca, et al.
Publicado: (2015)

QT Interval Prolongation Is a Novel Predictor of 1-Year Mortality in Patients With COVID-19 Infection
por: Banai, Ariel, et al.
Publicado: (2022)

Impact of lockdown on key workers: findings from the COVID-19 survey in four UK national longitudinal studies
por: Topriceanu, Constantin-Cristian, et al.
Publicado: (2021)

Weight Loss and Premature Death: The 1946 British Birth Cohort Study
por: Albanese, Emiliano, et al.
Publicado: (2014)

Validation of self-reported diagnosis of diabetes in the 1946 British birth cohort
por: Pastorino, Silvia, et al.
Publicado: (2015)

British Heart Rhythm Society Clinical Practice Guidelines on the Management of Patients Developing QT Prolongation on Antipsychotic Medication
por: Lambiase, Pier D, et al.
Publicado: (2019)

QT prolongation with methadone
por: Dhamija, Radhika, et al.
Publicado: (2008)

Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort
por: Masi, Stefano, et al.
Publicado: (2014)

Evaluating access to health and care services during lockdown by the COVID-19 survey in five UK national longitudinal studies
por: Topriceanu, Constantin-Cristian, et al.
Publicado: (2021)

Childhood cognitive ability and adult mental health in the British 1946 birth cohort
por: Hatch, Stephani L., et al.
Publicado: (2007)

Early-Life Overweight Trajectory and CKD in the 1946 British Birth Cohort Study
por: Silverwood, Richard J., et al.
Publicado: (2013)

Adiposity, Telomere Length, and Telomere Attrition in Midlife: the 1946 British Birth Cohort
por: Wulaningsih, Wahyu, et al.
Publicado: (2018)

Interleukin-6 Elevation Is a Key Pathogenic Factor Underlying COVID-19-Associated Heart Rate-Corrected QT Interval Prolongation
por: Lazzerini, Pietro Enea, et al.
Publicado: (2022)

Antihypertensive Medication Use and Its Effects on Blood Pressure and Haemodynamics in a Tri-ethnic Population Cohort: Southall and Brent Revisited (SABRE)
por: Hughes, Alun D., et al.
Publicado: (2022)

QT prolongation in the STREAM Stage 1 Trial
por: Hughes, G., et al.
Publicado: (2022)

Antipsychotic Medication and QT Prolongation
por: Chohan, Paramdip Singh, et al.
Publicado: (2015)

Psychiatric disorder in early adulthood and risk of premature mortality in the 1946 British Birth Cohort
por: Henderson, Max, et al.
Publicado: (2011)

Carotid atherosclerosis in people of European, South Asian and African Caribbean ethnicity in the Southall and Brent revisited study (SABRE)
por: Anbar, Rayan, et al.
Publicado: (2023)

Recent Advances in Short QT Syndrome
por: Campuzano, Oscar, et al.
Publicado: (2018)

Sex differences in long QT syndrome
por: Díez-Escuté, Nuria, et al.
Publicado: (2023)

The non-cancer mortality experience of male workers at British Nuclear Fuels plc, 1946–2005
por: McGeoghegan, Dave, et al.
Publicado: (2008)

Lifelong socioeconomic position and physical performance in midlife: results from the British 1946 birth cohort
por: Strand, Bjørn Heine, et al.
Publicado: (2011)

Childhood Stunting and Mortality Between 36 and 64 Years: The British 1946 Birth Cohort Study
por: Ong, Ken K., et al.
Publicado: (2013)

The relationship between affective symptoms and hypertension—role of the labelling effect: the 1946 British birth cohort
por: Tikhonoff, Valérie, et al.
Publicado: (2016)

MUC5AC and inflammatory mediators associated with respiratory outcomes in the British 1946 birth cohort
por: Johnson, Lauren, et al.
Publicado: (2013)

Physical Activity Across Adulthood and Bone Health in Later Life: The 1946 British Birth Cohort
por: Muthuri, Stella G, et al.
Publicado: (2018)

Dietary glycaemic index and cognitive function: prospective associations in adults of the 1946 British birth cohort
por: Philippou, Elena, et al.
Publicado: (2018)

Metabolic correlates of late midlife cognitive outcomes: findings from the 1946 British Birth Cohort
por: Green, Rebecca, et al.
Publicado: (2021)

Case Report: QT Prolongation and Abortive Sudden Death Observed in an 85-Year-Old Female Patient With Advanced Lung Cancer Treated With Tyrosine Kinase Inhibitor Osimertinib
por: Kondo, Moë, et al.
Publicado: (2021)

Beyond a prolonged QT interval
por: Bitar, Zouheir Ibrahim, et al.
Publicado: (2013)

QT Prolongation due to Graves' Disease
por: Kulairi, Zain, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_dppeebu9roejg57n8k4hp4m7rq