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Enantioselective bromination of axially chiral cyanoarenes in the presence of bifunctional organocatalysts

Enantioselective bromination of axially chiral cyanoarenes bearing high intrinsic rotational barriers via dynamic kinetic resolution using bifunctional organocatalysts is reported. Sequential addition of a brominating reagent in several portions at an optimized temperature was effective in accomplis...

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Detalles Bibliográficos
Autores principales: Wada, Yuuki, Matsumoto, Akira, Asano, Keisuke, Matsubara, Seijiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072646/
https://www.ncbi.nlm.nih.gov/pubmed/35527922
http://dx.doi.org/10.1039/c9ra05532k