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Natural transformation allows transfer of SCCmec-mediated methicillin resistance in Staphylococcus aureus biofilms

SCCmec is a large mobile genetic element that includes the mecA gene and confers resistance to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus (MRSA). There is evidence that SCCmec disseminates among staphylococci, but the transfer mechanisms are unclear. Here, we show that two-c...

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Detalles Bibliográficos
Autores principales: Maree, Mais, Thi Nguyen, Le Thuy, Ohniwa, Ryosuke L., Higashide, Masato, Msadek, Tarek, Morikawa, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072672/
https://www.ncbi.nlm.nih.gov/pubmed/35513365
http://dx.doi.org/10.1038/s41467-022-29877-2