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Natural transformation allows transfer of SCCmec-mediated methicillin resistance in Staphylococcus aureus biofilms
SCCmec is a large mobile genetic element that includes the mecA gene and confers resistance to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus (MRSA). There is evidence that SCCmec disseminates among staphylococci, but the transfer mechanisms are unclear. Here, we show that two-c...
Autores principales: | Maree, Mais, Thi Nguyen, Le Thuy, Ohniwa, Ryosuke L., Higashide, Masato, Msadek, Tarek, Morikawa, Kazuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072672/ https://www.ncbi.nlm.nih.gov/pubmed/35513365 http://dx.doi.org/10.1038/s41467-022-29877-2 |
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