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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies

Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. Metformin shows anti-tumor activities in several cancer types. How...

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Detalles Bibliográficos
Autores principales: Alanazi, Fawaz E., As Sobeai, Homood M., Alhazzani, Khalid, Al-Dhfyan, Abdullah, Alshammari, Musaad A, Alotaibi, Moureq, Al-hosaini, Khaled, Korashy, Hesham M., Alhoshani, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072704/
https://www.ncbi.nlm.nih.gov/pubmed/35528855
http://dx.doi.org/10.1016/j.jsps.2021.12.014