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IL1 Pathway in HPV-Negative HNSCC Cells Is an Indicator of Radioresistance After Photon and Carbon Ion Irradiation Without Functional Involvement

BACKGROUND: Treatment of locally advanced HPV-negative head and neck squamous cell carcinoma (HNSCC) with photon radiation is the standard of care but shows only moderate success. Alterations in response toward DNA DSB repair, apoptosis, and senescence are underlying determinants of radioresistance...

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Detalles Bibliográficos
Autores principales: Tiwari, Dinesh Kumar, Hannen, Ricarda, Unger, Kristian, Kohl, Sibylla, Heß, Julia, Lauber, Kirsten, Subtil, Florentine S. B., Dikomey, Ekkehard, Engenhart-Cabillic, Rita, Schötz, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072779/
https://www.ncbi.nlm.nih.gov/pubmed/35530351
http://dx.doi.org/10.3389/fonc.2022.878675