Imatinib Mesylate Reduces Neurotrophic Factors and pERK and pAKT Expression in Urinary Bladder of Female Mice With Cyclophosphamide-Induced Cystitis

Imatinib mesylate is a tyrosine kinase inhibitor that inhibits platelet-derived growth factor receptor (PDGFR)-α, -β, stem cell factor receptor (c-KIT), and BCR-ABL. PDGFRα is expressed in a subset of interstitial cells in the lamina propria (LP) and detrusor muscle of the urinary bladder. PDGFRα +...

Descripción completa

Detalles Bibliográficos
Autores principales: Perkins, Megan, Girard, Beatrice M., Campbell, Susan E., Hennig, Grant W., Vizzard, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072830/
https://www.ncbi.nlm.nih.gov/pubmed/35528149
http://dx.doi.org/10.3389/fnsys.2022.884260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9072830/
https://www.ncbi.nlm.nih.gov/pubmed/35528149
http://dx.doi.org/10.3389/fnsys.2022.884260

Ejemplares similares